Ugly Truth

Status
Available

Description
Hypoglycemia is the most serious and common adverse effect of diabetes therapy and is most common in patients taking insulin or sulfonylureas. The risk of hypoglycemia-related ED visits and hospitalizations is increased in those 75 and older and is associated with an increased risk of falls. The American Diabetes Association recommends de-intensification [A1C 7.5% – 8.5% ] for older patients at risk of falling due to hypoglycemia, such as those with multiple chronic illnesses, taking insulin, with cognitive impairment, or limited self-management skills.

References

1. McCoy RG, Lipska KJ, Van Houten HK, Shah ND. Association of cumulative multimorbidity, glycemic control, and medication use with hypoglycemia-related emergency department visits and hospitalizations among adults with diabetes. JAMA Netw Open. 2020;3(1):e1919099.

2. Kachroo S, Kawabata H, Colilla S, et al. Association between hypoglycemia and fall-related events in type 2 diabetes mellitus: analysis of a U.S. commercial database. J Manag Care Spec Pharm. 2015;21(3):243-53.

3. American Diabetes Association. Diabetes Care 2020 Jan; 43(Supplement 1): S152-S162

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